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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8059ddfd1e2053fc580aa7b11d90c9412b8829eaf3bd50d84cdb4a6f78eb577c' 
  AND token = '7I0IhpHj1OOJY3U18WigAnBoDQy8193Td74okgqTv8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}