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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b6a64508acc9e7ec30bb648fbd69688254aba26fbcaddfd500242df9100a481' 
  AND token = 'Lkt7YaQOI4uMoQHawdVWiEwOp6g3LMBh4aGEhOX0L0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}