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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec15a39e2e515855ab5f3dd5cec55488071b26011d245a43a9fffd5e222cc72' 
  AND token = 'ksHFBHdRPStlRtRx8QxrhubLzbJiwCSC5a5Ze2L8Eyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}