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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a195a8e8481e5b340cdda1ee67439c37e7c8da5849d006f27bd475f9808fc0' 
  AND token = 'kwDbOZEyYd57bf0CnvTFQNPSqf/tuS3/myvwxJpyEMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}