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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78da3c284a7c28801d8c285d1a5a71987136a163ec526d2144c71bf18965aa4a' 
  AND token = 'zsGXd3qpzUJtMsxAyDpc/VtF9LUhsup27oiF9h1FcNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}