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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5998db43d552642ee894a18475fce30f51a476373f33e777b1a6092492bd346f' 
  AND token = 'XXpkWoTW+pKPmyaeiWeJeiE0KD7yS/SswoJmfCMAXoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}