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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a9384c5e0d4a66ffa1e9a96c8c2fb24ef7f88eaa009ed560e859d834975548c' 
  AND token = 'kxeUB2uYxyYCVnrQFTCNCQmD0+lOOGmAoV1Yg3S6XqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}