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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41e41f12409c8b357e2f2e37ca3632d520e1633623cd5a0476df737023e79990' 
  AND token = 'V3BMq01teFbZtRSpYrqh4OUxJtNDmpz/2oHUW20amjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}