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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f821f81c1c420365b6f3b614ea2aafb9013d30be6dfa040a42626eb41d1418b4' 
  AND token = 'APzV5/83U2Le8Gjks5+LFPigNdQr2RaieL/DiwWa8xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}