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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f7a5343055f06b9f7714376e6c88e687b01c952a6edc2cbc3dff2e8e0043269' 
  AND token = 'UdXVp2AvNPkOBIQC4ltkt5TcnXKU1Na5bHMOdY08pCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}