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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed22ef7eb502b27e6f8d7d3cff91d347f2fde281f0ba86fa7d25b66895b5a882' 
  AND token = '4yrYyD7jHxu9noQjQPrxQ77rZ4KEJqrOS4ctBsOcu6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}