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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '704c748286d1f2d81c2a47058781b506f9cc2d8dc8fe483cf204204ffb4c24e8' 
  AND token = 'MdPRE408DZWMHeaSuKgsipvFRQNpsKd0zh2BWUXrWMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}