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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '189a8fa707cf27c9c5d6dc4d35409b05ef5d26d5812ea083ffa8a165f1346ac0' 
  AND token = 'Ttu4jSKpd7V5XKuHcQAkyVxRUYgZRDnelukgki4V8RE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}