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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '048c8777f5f1ad043ea09f5a00707847ea9095db95b454f20ea7c823cd35a66f' 
  AND token = 'R6EPPXG4+gAdQCk7sABzrwZRPPe2MJp8qLiFSrcgUaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}