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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae9e706fd55f6e56b8628b5e751548f9cbff5e3dae93e48c254e882cfc3d35c2' 
  AND token = 'j2HHZdmzAnWSEUR1hzqPa9FiOXjRO7H+fqtiHfXz/kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}