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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d273a177a2b406866fe9fc304dbee6f8d669b8356b1c8b6c92b876f22d839a6' 
  AND token = 'KegT9ZWk7CFC3i6G76tsS/xnBgBRanWy4XGK8UpzeMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}