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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d64b0a8f1dc1c2cc22382525bb0ec6bfeb3ee517859e28717ff03b5a8f25e41' 
  AND token = 'fgiGMPuYlIiocNO2IsprNIxGi0s7SXJjr8w3bw693mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}