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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a066832cfcd0e32b0360dd67304f1fe379f14a9f00edc3e5a83c3bf2db925ff4' 
  AND token = '1gQgAZseaTysg/CoLHrV6KofgjQ+vgp8kyxc7vm1vd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}