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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1decd7ace80841d7622d8d2712b6be9f23869fd57d0036298b5fba1840c7e421' 
  AND token = 'G5NqdHeFrOEBwMuDlsp3AUNbRV8pq+D8WkLVnwUGWu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}