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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a64b5e194b6f04885dfe4f5787f94e3fb00360b467b7f3bc683a2724447f7097' 
  AND token = 'Jxz50U8zIPFXeKJ2SgLkxKyAchiOamFmKBL/2WV1PUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}