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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fa640d5a7036804f0b2bd0e1d77fa5b4a89300dd10848a7811129f4f8ca14c9' 
  AND token = 'B+U19oLXevSmAI9v5XQvxQ8zU9itXSB8K7ISdEGpgQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}