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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a531a69cab2080b2d62ef8e00c52552e24bebfd18a94d0301f5a59b875d4fce3' 
  AND token = 'jOaG9Ncl92Y7ju+kAubBTkH7Sqcu5DQceyyJgRfZnK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}