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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6317b7b274e0aa3e887c47990099bea4cb6f55b1f6f901129f618b017994bec9' 
  AND token = '5ndYZJLvGl91RRTs7WN6YXZk1FwNGWid90ZvypoqcVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}