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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e0f7eb42498f8e6c688f7d8a651dddbed2144b059544126539b3802f60ddc46' 
  AND token = 'rO9w4CpVUHfHAr/7t6o7k6vETRMYgE977Ql2Q+q1CeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}