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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2d18d7ec65c9eeec8758ac38fe08bf9ed7cef28edd98b3883a631d624fef787' 
  AND token = 'FLMttDw4WY9SR6gekgSm/YJeJVpwOMkK6jbw2vK6U14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}