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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24fd0bf8367dfbe2b89c8edc455b6491caf3b30620291c4e27100ad813edbaa2' 
  AND token = 'spnXryrFwK/W2Lg1Wu8bvv2PpYv6TrS6DH1LgJN2Xcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}