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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e56fd8d7f65c605a337ad9bb86f5f9b6c07db2d2ce9ef64a991890af819b1d2' 
  AND token = 'VbMxV6IQ+IEY5KLGxkLdVUPTN6/vntoD+C8D9Vo7k60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}