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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64f791d900357920fa4e7d150b858b188a4f487c75aa7bfc59d66eb24bdeb020' 
  AND token = '6nxgV+Lcx26s6SvsTZBsy2Qu7FwiOgJqVSkoeXr4vJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}