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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a6d3faa9807503076f7c9b094ce5a26a1345edb1a37d57d8bd6eb20c2e32a8' 
  AND token = 'rA39RuM5CvXakWVZ+WbAbSD2TDnA0iSaNDW0TsBvzQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}