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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a04d53c3fac1632a785b3949f741fb502cf1ceb29613cd73073010fe0edde54' 
  AND token = '+BbUY2M0o4dAH9D3GfcPWPMgxj8O+EYaM3tlnEZnUlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}