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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dd465ada1d9b7e1ea801e4d8d3f744fa0d7343d2664681baf01087762ef3db3' 
  AND token = 'F4eqZaWnHhwkpegJJ5n/n+BLQaOWj4oRYK1jhq9Zo00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}