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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d71eabd78e59674831da354e5d7ac66f623aa4e1d357dd1dc433a575826784b' 
  AND token = 'LmuRwKTWBr95TOGRL6I2DnLqx3WClVjNvsBq8Ut7biI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}