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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55cb050ccbf132033f2438cb2cb3f60f87a825582b6fc5d35c024003090163e2' 
  AND token = 'aN1Eqqro4lGby2XxJM5CWGUNPpbs9nvIRmSFGmuyVS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}