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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ee34975093a26b299047e33568e1e991da798c98f4ce8f29ed57aa963aa5fcf' 
  AND token = '5YNoPEyWA8bPzE1RF8zgGDiErKbPMGQ95qWdD5Fdqeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}