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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60ba36bdf5cb792bf67153f42fd48de2beda2a485fa28c29021a52b0f2233e30' 
  AND token = 'IkxWWdG8eMTn9oO1ow0gMdBS3ioLI3XnNlt5sVt/Re8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}