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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '972ab9b354d8dc334b2db45d8cd98ff20555ab8b642c1f2165637aefbc09d7f8' 
  AND token = 'Msu6kHDSJ56jWxHFmPFl9FDbpYfUdrpBIisAQVlMUVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}