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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e2ad2c740b9f59ec04c563f60a5f16d96cfbdc112a5df67d622f7e91edb03f' 
  AND token = 'IW2qBPq4eaLj8YkKRRt/LSXyIy+jyuA+sIOeyrKPNQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}