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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8b25a7712860ed51bc5bc825d53b0250594046260b1762932326908074aa169' 
  AND token = 'HBGSgZIUhwk3lLCQ5/wstyH1icQGWaGyBXP2tL+S7is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00075

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}