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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b5d57bcb017b9d8d24c2eb1dcaf5b485f3e34e6f9680be3d7406cc50a61a67' 
  AND token = 'WxuV4aY67mVCHtA0xIFi00e0X1xZv4U7tXgFP8PpbaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}