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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5ef441848d5a4eca6c7cf708d6bbe9844410e1cbe1dd665bcb534326ef9479e' 
  AND token = 'UZeDgKO8GarIPNRUeN4lQmityQXATTmC0vdAvreW8xQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}