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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241842c17701fbb7b72e38b2899c20577d8b7f41b9ad1bc9d9f1c51015ae143d' 
  AND token = 'jJFaO1ZceHMSM8K9eTWei9aSfu3p2YHYv3/7AS3PNOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}