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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5678c4eab10f6dc54d674a65b279e544ab38ca8019664b1c92a33c594743b360' 
  AND token = '4DU0USmaazuBV48QHqcrUkollbQbsTVMVOIV+giwtlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}