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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de790d09668276991c7628221ae184a4d56df2dff7e48d01d2f1d74982ee0299' 
  AND token = '2uuhH150d0vR3jwKWYiKTOJY6krqjvm00votcLFFz/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}