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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34786a87bcb0375853156b837e64269d717e006837b4809a37b23f0a9869c397' 
  AND token = 'KiXSt5ZgyNtZ6h2TCZR2ItLCCOXWOWFU8QwRBVkgkhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}