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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38bb29454b39673a649f930951de77dc587958573f5bfbb7ff29157ae63aedb5' 
  AND token = 'RpmDi8mjFI4Lx6a+vk8/ij1lrL4Z8qcaATAtKbbwhao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}