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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ffd4704ecf7fc68aa7a788cfb7e6205bc0ae488fd2685bada8101376d5d3333' 
  AND token = 'Y+e9bZ4b6FJQxom1PYxZYyuq8u31cOVrWp1Eg/NkeRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}