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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46cefe45b9bfd4dd580daca3da6d559afce6d2c9a3d7fe5f23be70c96e0351d8' 
  AND token = 'TSYX6MsCHO7womRTMz3yG8M1zUix2nbwYFRBGat1XPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}