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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f5fe53e0dfceeff1d037cbb942f6ee059b24ae80db92c57f7e052729ad02ebe' 
  AND token = 'ZUQ9VX+902zS/AOikLtOH1+H9Y2H3PKosNCUA6neHZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}