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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7d562204d504d9ea399068e4ee7f104e5e9854f638b14f0e3e1487966e69dc4' 
  AND token = 'RjFUPzam1+yyBqya7UfM8cLi0jL/eVmiUcht1A5WDrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}