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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2a11f4d67bd77f96c7ac878786a71f498b8a6a5eab834a68f89daaa403e7ded' 
  AND token = 'Wu4QGuaWzFtLCff2Uqw0AD8TwHehdzHm5uSmpWG6zLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}